P-shot® London - A safe Erectile Dysfunction Treatment

Good candidates for a P-Shot® include those suffering from erectile dysfunction, Peyronie’s disease, Penile Lichen Sclerosus, lack of sensitivity or desire, premature ejaculation, and shrinkage of penile tissues. Essentially, anyone seeking to improve their sexual performance could benefit from a P-Shot®.

Dr Nadia Yousri, an expert in men’s and women’s sexual health, performs the P-Shot® procedure. Her qualifications include FRCOG, MRCOG, PhD and MSc. As an authorised P-Shot® provider, she has performed thousands of P-Shot® procedures in London, offering personalised medical care with a commitment to professional ethics, discretion and patient privacy.

Your appointment begins with a comprehensive clinical assessment and completion of the relevant medical forms to establish your suitability for treatment. Dr Nadia provides individualised counselling, discussing potential benefits, risks, alternatives, realistic expectations and aftercare before obtaining your informed consent.

If treatment proceeds, a blood sample is taken and spun to prepare the platelet-rich plasma (PRP) concentrate. A topical anaesthetic cream is applied to help minimise discomfort before the PRP is expertly injected into specific locations in the penis. Some discomfort may still be felt, as individual sensitivity varies.

The PRP preparation and injections take approximately 30–40 minutes, with additional time allowed for assessment, counselling and anaesthetic preparation

The P-Shot® uses PRP prepared from your own blood, reducing the likelihood of reactions to the PRP itself. Published studies have generally reported good tolerability, although safety evidence is still developing. Temporary discomfort, swelling or bruising may occur and usually settle within a few days, with little interruption to routine daily activities. Individual recovery varies, and specific aftercare advice is provided.

As with any injection procedure, bleeding and infection are possible. During consultation, Dr Nadia reviews your medical history, medication and any previous reactions to local anaesthetics or other products used during treatment.

Please tell the doctor if you take blood-thinning medication, as this may increase bruising or prolong oozing at injection sites. Do not stop or alter prescribed medication yourself; any necessary changes will be discussed with you and agreed with your prescribing clinician.

Research into penile platelet-rich plasma (PRP), used in the P-Shot®, has reported encouraging improvements, although there is no single established success rate. Results depend on the condition being treated, the treatment protocol and how improvement is measured.

For erectile dysfunction: In a randomised trial by Poulios and colleagues, 69% of men receiving PRP achieved a clinically meaningful improvement in erectile function at six months, compared with 27% receiving placebo. This means approximately seven in ten treated men experienced a meaningful improvement—not that erectile function improved by 69%. The European Association of Urology (EAU) also cites another trial reporting meaningful improvement in 70% of PRP recipients, compared with 16% receiving placebo. However, a separate trial by Masterson and colleagues found no significant advantage over placebo. The EAU therefore recognises promising findings but currently recommends penile PRP for ED only within clinical trials, pending stronger evidence. [1–3]

For Peyronie’s disease: Early studies suggest that PRP may reduce penile curvature. The EAU describes average reductions of approximately 10–16 degrees in preliminary studies, while emphasising that effectiveness remains unproven. Dr Charles Runels, the developer of the P-Shot®, reports 75–80% success for Peyronie’s disease on his official website. However, that article does not define “success” or provide the supporting study details, so this figure should not be interpreted as the percentage of men achieving complete straightening. [4,5]

For penile lichen sclerosus (LS): Early research has reported improvements in symptoms and quality of life. A study involving 43 men and 51 women reported reduced symptoms six months after PRP treatment. A separate small study in men reported symptom relief but minimal visible skin changes. These findings support further investigation, although a reliable success percentage or consistent improvement in skin texture has not been established. [6,7]

These findings offer grounds for cautious optimism. They describe outcomes in particular research groups and do not guarantee the same result for every patient. Your consultation includes discussion of the evidence relevant to your condition and what improvement could realistically mean for you. (See links to references below)

The P-Shot® aims to support tissue repair and improve erectile function, with encouraging improvements reported in some clinical studies. The degree and timing of improvement vary between men. Preliminary research suggests that age, smoking, the initial severity of erectile dysfunction and associated conditions such as diabetes or hypertension may influence the response.

Dr Nadia’s consultation also considers the cause and duration of your symptoms, general health, lifestyle and previous treatments, helping to assess suitability and establish realistic, personalised expectations. Some men experience meaningful improvement, while others experience a smaller change or no benefit. Larger studies are needed to clarify who is most likely to benefit and which treatment course offers the best results.

The timing of improvement after a P-Shot® varies between individuals. Some men may notice improvement within the first few weeks to three months, although a response is not guaranteed.

Clinical studies have reported improvements at one-, three- and six-month follow-up assessments after completing treatment. According to the developer of the P-Shot® procedure, Dr Charles Runels, improvement generally begins around three to four weeks after treatment, with fuller effects at approximately three months. These times provide a guide rather than a fixed expectation, as the response and degree of improvement vary.

Treatment may involve a course of sessions rather than a single P-Shot®, depending on the condition being treated and your individual assessment. Dr Nadia will discuss the proposed number and spacing of sessions during consultation. Your progress is reviewed at follow-up to assess whether further sessions are appropriate.

The developer of the P-Shot® procedure, Dr Charles Runels, reports that approximately 60% of patients are satisfied after one session, rising to 85% after a second. These figures reflect his reported observations rather than results from a controlled clinical trial.

The P-Shot® may be considered as part of an individualised treatment plan, alongside other appropriate options. For selected men with erectile dysfunction, this may include low-intensity shockwave therapy or prescribed medication following clinical assessment.

Some studies have reported encouraging improvements when penile PRP is combined with shockwave therapy, although larger trials are needed to confirm the additional benefit. During consultation, Dr Nadia reviews your condition, previous treatments and goals to discuss whether a combined approach is appropriate, including its potential benefits, risks and alternatives.